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Email:sales@ruixibiotech.com
Tel.:02988811435
CCT245737 CAS：1489389-18-5
CCT245737
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-C-2074 | 50mg | 305.00 | + Add to cart |
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| R-C-2074 | 100mg | 500.00 | + Add to cart |
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| R-C-2074 | 200mg | 800.00 | + Add to cart |
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Product description
CCT245737 is a potent, selective and orally active checkpoint kinase 1(CHK1) inhibitor.CCT245737 showed CHK1 IC50=1.3nM,CHK2 IC50=2440nM,G2 check point abrogation IC50=30nM.Mouse F(oral)=100%.CCT245737 demonstrated a favorable physicochemical,PK,and PD-efficacy profile.The serine-threonine kinase CHK1 is a critical component of the cellular response to DNA damage,especially the repair of DNA breaks arising during replication or caused by DNA damaging chemotherapies and ionizing radiation.
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| purity | >95% |
| PDI by GPC | <1.5 |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 3 weeks |
| Stability | 1 year |
Document
msds---CCT245737 Related Product
RuixiBiotechCo.Ltd /KamulinBiotechco.ltd
Add: Room 20F 2002, Meiyuan Building, Yanta District, Xi’ an City, Shaanxi Province 710061 China
Tel: 02988811435
Fax: (86-29)8881-1435
Email: sales@ruixibiotech.com
Web: http://www.ruixibiotech.com
